Hi Katherine,
Thank you for posting in MSDN forum.
Could you please tell us when this box occurs? Once running some application or just pop up from time to time?
You could have a try to navigate to path:
c:/Microsoft.Net\Framewok\v2.00727Installuti.exe
execute this setup.exe to check if the window comes up again.
Best Regards,
MSDN Community Support
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