Hi known MSCRM,
I have experience with this type of environments and organization size.
In my opinion your hardware looks perfectly fine for CRM 2011, but performance wise, depends a lot of what you do with CRM and specially how many concurrent connections you actually have? and what is the current load on this servers with those concurrent
users? How many workflows and plugins you may have and how often they run. From what you wrote, you don't have separate asynch servers, so I assume you don't rely heavily on workflows etc.
Also do you rely heavily on javascript on the entity forms? if you have 10 000 users you may have users across different countries/regions, CRM 2011 latency can deteriorate due to the increase in the amount of data loaded. If you haven't invested in wan-optimizers
e.g. Riverbed, you may want to consider these solutions.
SQL 2012 has performance improvements, and will probably be a nice upgrade when it comes.
Visit my blog for CRM material, improving performance, kerberos, IFD, development tips, etc. :) http://quantusdynamics.blogspot.com
