Live Mesh Beta or Windows Live Mesh?
If it is the latter, for discussion of the new Windows Live Mesh (formerly Sync), (as well as the released Live Sync version) go here:
http://windowslivehelp.com/forums.aspx?productid=24
In either case, did you uninstall and reinstall the client software?
-steve
~ Microsoft MVP Windows Live ~ Windows Live OneCare| Live Mesh|MS Security Essentials Forums Moderator ~