Yes, there's no problem doing these. Each deployment will create its own 5 AD groups (PrivUserGroup, ReportingGroup etc) with a guid for a suffix. I'd suggest creating separate Organizational Units for these groups for each deployment to make it easy to
identify the groups.
Each CRM deployment will need to be installed on a separate SQL instance (as each CRM deployment has it's own MSCRM_Config), and a separate Reporting Server if you use the Reporting Server Connector (note this has to be a separate server, not just a separate
instance)
Otherwise there are no other issues
Microsoft CRM MVP -
http://mscrmuk.blogspot.com http://www.excitation.co.uk