jim has pointed you to the answer for the Security Center issue.
For your backup issue, if you recently moved your backup drive from one USB port to another, this can happen.
Try resetting your backup plan -
http://social.microsoft.com/Forums/en-US/onecarebackupandrestore/thread/5f18a60d-add4-4ff2-87cf-021db7e81917if that does not help, please contact support
How to reach support (FAQ) - http://social.microsoft.com/Forums/en-US/onecareinstallandactivate/thread/30400b52-7f26-4ba0-bc18-17e305329d90
-steve
Microsoft MVP Windows Live / Windows Live OneCare, Live Mesh, & MS Security Essentials Forums Moderator