Loading cases in CRM 2015 in IE which went from 3 sec to load to over 30 sec after we upgraded from 11.0.45 to 11.0.46 and the same behavior when we upgraded to 11.0.47. We have applied all of the IE and Security updates for September and October already.
We have also tested pulling down the firewall and putting back up with no difference. There are no add-ons enabled in the IE users we tested.
The problem does not appear in Chrome as it will load in about 3 sec.