Hi maxcammy,
If you make a Full disk image on the new hard drive, it should work, but I can not be positive as I'm not familure with that backup software.
If Vista came pre-installed on that computer, it should re-activate itself without issue (as long as you have not changed out the motherboard.
If Vista did not come pre-installed, you will most likely need to reactivate by phone. when you call, you will first hear an Automated Voice that will try to Activate Vista for you. If the Atomated Voice gives you an option to talk to a Live Activation Rep, select that option. If not, do not enter any numbers. This should force the Automated Voice to transfer you to a Live Activation Rep. Trying to Activate thru the Automated Voice will not work, in your case, only thru the Live Activation Rep will your Activation be successful.
Thank you,
Darin Smith
WGA Forum Manager
p.s. I deleted your other post because it was a duplicate of this post.