You posted to the off topic forum for Windows Live OneCare.
Your question may be better posed to one of the forums here.
Vista: http://social.answers.microsoft.com/Forums/en-US/category/windowsvista
XP: http://social.answers.microsoft.com/Forums/en-US/category/windowsxp
Windows 7: http://social.answers.microsoft.com/Forums/en-US/category/windows7
My recommendation?
You can use the free Microsoft Security essentials for malware protection - http://www.microsoft.com/security_essentials/resources.aspx
You will need to remove your prior security software before installing MSE.
Additional recommendations:
Make sure that the Windows Firewall is enabled.
Make sure that all important/critical updates, including service packs for the operating system and programs are installed from Microsoft Update (Windows Update).
Make sure Internet Explorer is at version 8 and updated with all patches.
In Internet Explorer 8, use the SmartScreen Filter.
Make sure that IE Internet Security settings are at least set to medium-high (default).
Enable the pop-up blocker in IE.
On Vista and Windows 7 make sure that User Account Control (UAC) ON and not running with elevated privileges.
Make sure that Windows Automatic Updates are set to at least notify, but the preferred setting is to download and install automatically. If you update manually, be sure to update as soon as possible after being notified of available updates.
Make sure that installed applications, especially Adobe Acrobat, Adobe Flash, and Java are at their latest versions. Many vendors are regularly updating and patching for security holes.
Never click through links from unknown sources and use caution even if they are from a "trusted" source.
Never open unsolicited email attachments.
Practice safe web browsing.
-steve
~ Microsoft MVP Windows Live ~ Windows Live OneCare| Live Mesh|MS Security Essentials Forums Moderator ~