In this case a double whammy. We don't support 4 bit per sample in a TIFF file, nor do we support palettized tifs.
bits per sample: we only support 8 or 16
samples per pixel: we support 1, 3 or 4
for photometric we support (1) monochrome black is zero or (2) RGB see http://www.awaresystems.be/imaging/tiff/tifftags/photometricinterpretation.html for a list of photometric interp.