I had IE8 Beta on my home machine running Vista SP1 and it didn't bring up the content window for my lesson (in this case Course 2276) either by clicking on the link for the lesson or the Begin/Resume/Reivew button under the Launch column. It didn't do anything except refresh the Content page that listed all the modules/lessons. I tried Emulate IE7 mode, restarted IE8 and that didn't work. Shut off pop-up blocker, same issue. Also added *.microsoft.com and *.microsoftlearning.com to trusted sites and no progress. I uninstalled IE8, restarted and now it works fine. Just thought you should know.