Having packet writing software such as Roxio or Nero running in the system tray can interfere with One Care's ability to identify your CD drive. Closing Roxio or Nero should resolve the issue. If closing these programs does not resolve the issue or if these types of programs are not present please contact support. How to reach support - http://social.microsoft.com/Forums/en-US/onecareinstallandactivate/thread/30400b52-7f26-4ba0-bc18-17e305329d90Jim - MVP Windows Live - Forum Moderator - Live One Care - Live Mesh - Microsoft Security Essentials