One way to handle this is to ask your Sales team or whoever generates quotes, to first revise the quote, open the product record that was discounted, select the override price button, and enter the discounted price. Another option is to just apply the discount to the revised quote and activate it if you don't need to track the discount at the product level. Once the changes are complete, the user should activate the quote and then you can convert the Quote to an Order. This will ensure that the Quote and Order contain accurate information.
If you only want to track the discounted product at the Order level, then before you close or Submit the Order, open the discounted product line on the Order record, select override price and make the change at the Order Product.
Best Regards,
Donna