Larry, is this with OneCare 2.0 beta or with 1.6? How does the Linksys NAS appear to Windows? Does it use a special driver and/or software support to be connected or is it configured as a simple network Share?
If this is the beta,
Please file a bug on Connect: https://connect.microsoft.com/site/sitehome.aspx?SiteID=168
See the Bug Submission Guide - http://connect.microsoft.com/content/content.aspx?ContentID=3480&SiteID=168 - for details on how to create and submit the Support Log zip file with your bug.
If this is 1.6 OneCare, it may be best to contact support -
Support for v1.6 is via the information here - http://forums.microsoft.com/WindowsOneCare/ShowPost.aspx?PostID=1183038&SiteID=2
And, yes, NAS devices *should* work on a system with OneCare, but it sounds like the software/driver for the drive may be blocked by OneCare's firewall.
-steve